No Meaning - Most & Least Affirming
To say that life has no meaning can be either most or least affirming.
If it comes out of an exclusive identification with our human self, it is most likely an expression of hopelessness and despair.
If it comes out of knowing ourselves as "groundless ground", as formless awareness, distinct from the world of phenomena, then it is an expression of realizing that everything is complete as it is. There is no room for less or more meaning. Everything just is, complete and perfect as is - beyond and including the polarity of completeness and incompleteness we find in the world of phenomena.